Variable viral clearance despite adequate ganciclovir plasma levels during valganciclovir treatment for cytomegalovirus disease in D+R- transplant recipients 英文论文文献.docVIP
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VariableviralclearancedespiteadequateganciclovirplasmalevelsduringvalganciclovirtreatmentforcytomegalovirusdiseaseinDR-transplantrecipients英文论文文献
Perrottetetal.BMCInfectiousDiseases2010,10:2
/1471-2334/10/2
RESEARCH ARTICLE
OpenAccess
Variableviralclearancedespiteadequate
ganciclovirplasmalevelsduringvalganciclovir
treatmentforcytomegalovirusdiseaseinD+/R-
transplantrecipients
NancyPerrottet1,OriolManuel2,FrédéricLamoth2,Jean-PierreVenetz2,RolandSahli3,LaurentADecosterd1,
ThierryBuclin1,ManuelPascual2,PascalMeylan3*
Abstract
Background:Valganciclovir,theoralprodrugofganciclovir,hasbeendemonstratedequivalenttoivganciclovirfor
CMVdiseasetreatmentinsolidorgantransplantrecipients.Variabilityinganciclovirexposureachievedwith
valganciclovi
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