Variants in KCNQ1 increase type II diabetes susceptibility in South Asians A study of 3,310 subjects from India and the US 英文论文文献.docVIP
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Variants in KCNQ1 increase type II diabetes susceptibility in South Asians A study of 3,310 subjects from India and the US 英文论文文献
Beenetal.BMCMedicalGenetics2011,12:18
/1471-2350/12/18
RESEARCH ARTICLE
OpenAccess
VariantsinKCNQ1increasetypeIIdiabetes
susceptibilityinSouthAsians:Astudyof3,310
subjectsfromIndiaandtheUS
LatonyaFBeen1,SarjuRalhan2,GurpreetSWander2,NarinderKMehra3,JaiRupSingh4,JohnJMulvihill1,
ChristopherEAston1,DharambirKSanghera1*
Abstract
Background:Polymorphismsinintron15ofpotassiumvoltage-gatedchannel,KQT-likesubfamilymember1
(KCNQ1)genehavebeenassociatedwithtypeIIdiabetes(T2D)inJapanesegenome-wideassociationstudies
(GWAS).Morerecentlyameta-analysisofEuropeanGWAShasdetectedanewindependentsignalassociate
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