Variants in KCNQ1 increase type II diabetes susceptibility in South Asians A study of 3,310 subjects from India and the US 英文论文文献.docVIP

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Variants in KCNQ1 increase type II diabetes susceptibility in South Asians A study of 3,310 subjects from India and the US 英文论文文献.doc

Variants in KCNQ1 increase type II diabetes susceptibility in South Asians A study of 3,310 subjects from India and the US 英文论文文献

Beenetal.BMCMedicalGenetics2011,12:18 /1471-2350/12/18 RESEARCH ARTICLE OpenAccess VariantsinKCNQ1increasetypeIIdiabetes susceptibilityinSouthAsians:Astudyof3,310 subjectsfromIndiaandtheUS LatonyaFBeen1,SarjuRalhan2,GurpreetSWander2,NarinderKMehra3,JaiRupSingh4,JohnJMulvihill1, ChristopherEAston1,DharambirKSanghera1* Abstract Background:Polymorphismsinintron15ofpotassiumvoltage-gatedchannel,KQT-likesubfamilymember1 (KCNQ1)genehavebeenassociatedwithtypeIIdiabetes(T2D)inJapanesegenome-wideassociationstudies (GWAS).Morerecentlyameta-analysisofEuropeanGWAShasdetectedanewindependentsignalassociate

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