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Variations in CCL3L gene cluster sequence and non-specific gene copy numbers 英文论文文献
Shresthaetal.BMCResearchNotes2010,3:74
/1756-0500/3/74
SHORT REPORT
OpenAccess
VariationsinCCL3Lgeneclustersequenceand
non-specificgenecopynumbers
SadeepShrestha1*,MawuliNyaku1,JeffreyCEdberg2
Abstract
Background:Copynumbervariations(CNVs)ofthegeneCCchemokineligand3-like1(CCL3L1)havebeen
implicatedinHIV-1susceptibility,buttheassociationhasbeeninconsistent.CCL3L1shareshomologywithacluster
ofgeneslocalizedtochromosome17q12,namelyCCL3,CCL3L2,and,CCL3L3.Thesegenesareinvolvedinhost
defenseandinflammatoryprocesses.SeveralCNVassayshavebeendevelopedfortheCCL3L1gene.
Findings:Throughpairwiseandmultip
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