Variations in CCL3L gene cluster sequence and non-specific gene copy numbers 英文论文文献.docVIP

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Variations in CCL3L gene cluster sequence and non-specific gene copy numbers 英文论文文献.doc

Variations in CCL3L gene cluster sequence and non-specific gene copy numbers 英文论文文献

Shresthaetal.BMCResearchNotes2010,3:74 /1756-0500/3/74 SHORT REPORT OpenAccess VariationsinCCL3Lgeneclustersequenceand non-specificgenecopynumbers SadeepShrestha1*,MawuliNyaku1,JeffreyCEdberg2 Abstract Background:Copynumbervariations(CNVs)ofthegeneCCchemokineligand3-like1(CCL3L1)havebeen implicatedinHIV-1susceptibility,buttheassociationhasbeeninconsistent.CCL3L1shareshomologywithacluster ofgeneslocalizedtochromosome17q12,namelyCCL3,CCL3L2,and,CCL3L3.Thesegenesareinvolvedinhost defenseandinflammatoryprocesses.SeveralCNVassayshavebeendevelopedfortheCCL3L1gene. Findings:Throughpairwiseandmultip

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