Vertebrate Hedgehog signaling cilia rule 英文论文文献.docVIP

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Vertebrate Hedgehog signaling cilia rule 英文论文文献.doc

Vertebrate Hedgehog signaling cilia rule 英文论文文献

Wilson and Stainier BMC Biology 2010,8:102 /1741-7007/8/102 CO MMENTA RY Open Access Vertebrate Hedgehog signaling: cilia rule Christopher W Wilson and Didier YR Stainier 1* 2 See research article: /1741-7007/8/65 be conserved from invertebrates to vertebrates [1]. function of Hh is to regulate the activity of Gli-family transcriptional regulators (Ci in Drosophila, Gli in vertebrates). In the absence of Hh signaling, Ci/Gli trans- criptional regulators undergo proteasome-dependent limite

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