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Vertebrate Hedgehog signaling cilia rule 英文论文文献
Wilson and Stainier BMC Biology 2010,8:102
/1741-7007/8/102
CO MMENTA RY
Open Access
Vertebrate Hedgehog signaling: cilia rule
Christopher W Wilson and Didier YR Stainier
1* 2
See research article: /1741-7007/8/65
be conserved from invertebrates to vertebrates [1].
function of Hh is to regulate the activity of Gli-family
transcriptional regulators (Ci in Drosophila, Gli in
vertebrates). In the absence of Hh signaling, Ci/Gli trans-
criptional regulators undergo proteasome-dependent
limite
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