“肌壁大部切除-子宫重建术”对卵巢功能影响的初步研究.pdfVIP

“肌壁大部切除-子宫重建术” 对卵巢功能的初步影响① 中文摘要 目的：研究“肌壁大部切除-子宫重建术”（major uterine wall resection and reconstruction of the uterus, MURU ）对卵巢功能的影响。 方法：根据超声子宫单侧肌壁厚度（前壁、后壁或宫底）或腺肌瘤最大直径将 患者分为轻、中、重三度。选取无生育要求的 16 例中、重度子宫腺肌病患者（观察 组）行MURU 术，并于术中放置LNG-IUS。另选取同期16 例子宫肌瘤患者（对照组） 行子宫肌瘤挖除术，观察两组术前、术后不同时段卵巢体积，窦卵泡计数及血清AMH 值的变化情况。 结果：两组手术均获成功，无术中及术后并发症；子宫肌瘤组术前卵巢体积， 窦卵泡计数及血清AMH 值与术后一月、三月、六月、十二月对比，差异均无统计学意 义（P＞0.05）。子宫腺肌病组术前卵巢体积，窦卵泡计数及血清AMH 值与术后一月、 三月、六月、十二月对比，差异亦无统计学意义（P＞0.05）。将两组卵巢功能分别在 术前、术后一月、三月、六月、十二月进行对比，差异无统计学意义（P＞0.05）。 结论：MURU 不影响子宫腺肌病患者近期卵巢功能，但长期影响，有待进一步追 踪、观察。 关键词：“肌壁大部切除-子宫重建术”；卵巢功能；子宫腺肌病 ① 国家自然科学基金）和贵州省自然科学基金（2014-1-65 ）资助项目。 2 The Possible Impact to ovarian function after MURU in Patients with Adenomyosis, a Preliminary Research [Abstract] Objective ：To observe the possible impact to ovarian function in patients with adenomyosis （AMS ） after major uterine wall resection and reconstruction of the uterus (MURU). Method ：Patients of adenomyosis were divided into three degrees as mild, moderate and severe levels according to the maximum diameter (MD) of single-side muscle thickness (front, back and bottom of uterine) or MD of adenomyoma by B-mode ultrasound device. 16 cases with moderate and severe patients were accepted and treated with MURU operation. Meanwhile, 16 cases patients with myomectomy were chosen as control group in corresponding period. The value of Anti-mullerian hormone (AMH) in serum,Ovarian volume(OV) and Antral follicle count(AFC) were measured and analyzed pre- and postoperative in different observing time both in two groups. Results ：All patients were successfully treated in two groups. No significant different values of AMH, OV, AFC were found in two groups Pre- and postoperative in different observing time