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Within-species lateral genetic transfer and the evolution of transcriptional regulation in Escherichia coli and Shigella 英文论文文献
SkippingtonandRaganBMCGenomics2011,12:532
/1471-2164/12/532
RESEARCH ARTICLE
OpenAccess
Within-specieslateralgenetictransferandthe
evolutionoftranscriptionalregulationin
EscherichiacoliandShigella
ElizabethSkippingtonandMarkARagan*
Abstract
Background:Changesintranscriptionalregulationunderliemanyofthephenotypicdifferencesobservedwithin
andbetweenspeciesofbacteria.Lateralgenetictransfer(LGT)cansignificantlyimpactthetranscriptionfactor(TF)
geneswhichdrivethesetranscriptionalchanges.AlthoughmuchemphasishasbeenplacedonLGTofintact
genes,theunitsoftransferandrecombinationdonotnecessarilycorrespo
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