含有药物活性物质的过渡金属配合物的合成剖析.doc

摘要 近几十年来，过渡金属配合物药物研究不断取得突破性成就，其在抗菌、抗肿瘤和抗病毒等方面都具有一定优势，具有很大的开发潜力和良好的应用前景。 本文基于分子设计的思想，以二价的Co、等为中心离子，1，4-双(咪唑-1-基)丁烷（bbi）、对羟基苯甲酸等为配体，合成了种金属配合物，并 Abstract In recent decades, transition metal complexes drug research breakthrough achievements unceasingly, its antibacterial, antitumor and antivirus, etc have certain advantages, has great development potential and good application prospect. In this paper, based on the idea of molecular design, with bivalent Cu, Co, Mn ions for the center, such as benzene tetracarboxylic acid, 1, 4 - double (imidazole - 1 -) butane (bbi), p-hydroxy benzoic acid a