CT灌注成像技术在肿瘤中的应用_谭泽兵.pdf

2008 18 2 　J Med Imaging Vol.18 No.2 2008 CT 1 2 2 谭泽兵 　综述,周顺科,张子曙 　审校 (1.　　　410073;2.　　　410011) 　　【　】　CT , , 。 , 、。CT 。CT , CT 、。 【】　;;;;;, X :R73;R814.42　　　:A　　　:1006-9011(2008)02-0191-04 Application of CT perfusion technique for the tumor 1 2 2 TAN Ze-bing , ZHOU Shun-ke , ZHANGZi-shu 1.Department of Radiology, The Hospital of National Def ence Uni ersity of Science and Technology, Changsha 4 100073, P .R .China 2.Department of Radiology, X iangya Second Hospital, Central-South Uni ersity, Changsha 410011, P.R.China 【Abstract】　Perfusion CT is a functional imaging technique that can rovide hysiological and metabolic information, and be used for microcirculation function evaluation in vivo.Tumor growth is recognized as relationwith neovascularization and increase of blood.Tumor angiogenesis is essential for tumor growth, invasion, and metastasis.Perfusion CT imaging technique is of value in study of tumor.This article reviewed the literature of the tumor erfusion CT imaging, summarizing its basic rinci les, a lications of qualitative diagnosis, thera eutic monitoring, rognosis evaluation and other as ects. 【Key words】　Tumor;Perfusion imaging;Qualitative diagnosis;Thera eutic monitoring;Prognosis evaluation;Tomogra hy, X-ray com uted 　　CT , 、 (central vol- [3] , ume rinci le) 。- , , , , 、。 。 CT , 1mg/ml [4] 25HU , 1mg 1ml CT 25HU, 、。 1979 , Leon Ax- 1mg 25HU/ml。 el[1] CT , , 。 , 。 (blood flow, BF)、(blood volume, [2] BV)、(mean transit time, MTT)、 1991Miles CT 。 80 , , CT, (time to eak, TTP)、(erme- 。90 , CT , ability surf