不同来源嗜水气单胞菌的抗菌素耐药性及耐药机制分析_宋铁英.pdfVIP

福建农业学报23( 2) : 119~ 124,2007 : 1008- 0384 ( 2008) 02- 0119- 06 F uj ian J ournal of A g r icult ural Sc iences 宋铁英, 陈 强, 郑在予, 李艳虹, 龚 晖, 林天龙 ( , 350003) : 40, 9, , 12 1 , 11 , ; , , 4e , : ; ; ; ; : S 9171 1 : A Antimicrobia-l resistance and Mechanism of Aer omonas Hy drop hil a S NG T ie-ying, CHEN Qiang, ZHENG Zai-yu, LI Yan-hong, G NG Hui, LIN Tian-long (B iotech nology I nst it ute of F uj ian A cademy of A g ric ult ur al Sc iences , F uz hou, F uj ian 350003, Ch ina) Abstract: Fourty A er omonas H y d rop h ila strains were isolated and/or collected from Russia and different areas in China at different time. All isolates were identified by their biochemical characteristics. Antimicrobial susceptibility of the bacteria to 9 different antimicrobials was tested. Results indicated that the antimicrobial-resistance of the A . H y dr op h ila strains was highly related to the antimicrobial usage in the field, from where the pathogens were isola- ted. By analyzing the correlation between the plasmid and its host bacterium. s antimicrobial-resistance, it was found that 11out of the 12 bacteria strains, which harbored more than one high copy plasmids, exhibited high antimicrobi- al-resistance. In contrast, the strains containing no or low copy plasmids showed no correlation between their anti- microbial-resistance ability and plasmids. The antimicrobial-resistance stability test indicated that long-term storage of the bacteria at 4e could reduce their resistance to antimicrobials. n the other hand, a series subculturewith re- peated freeze-thaw cycles had no effect on the bacteria. s antimicrobial-resistance. Key words: A er omonas hy dr op h ila antimicrobia-l re