临床药师参与2例夫西地酸乳膏用于局部感染耐甲氧西林金黄.PDFVIP

临床药师参与2例夫西地酸乳膏用于局部感染耐甲氧西林金黄 色葡萄球菌患者的治疗分析 ＊ # 林 瑶 ，强栓虎，薛晓娟，高 亚，赵 洁，张耀峰，王晓娟（第四军医大学口腔医院药剂科，西安 710032） 中图分类号 R 192.8；R978.1；R969.3 文献标志码 A 文章编号 1001-0408（2014）02-0191-02 DOI 10.6039/j.issn. 1001-0408.2014.02.33 摘 要 目的：为局部感染耐甲氧西林金黄色葡萄球菌（MRSA ）患者药物治疗提供参考。方法：介绍临床药师参与2例局部感染 MRSA 患者的诊疗经过，对其治疗方法、效果、原因进行分析。结果：2例患者感染MRSA 均为局部感染，无全身症状，不具备全身 性使用抗菌药物的条件。临床药师提出药学建议，可局部用夫西地酸乳膏涂抹。使用夫西地酸乳膏3～5d 后，患者局部症状明显 缓解，感染得到有效控制。结论：夫西地酸乳膏对于局部感染MRSA 但无全身感染症状的患者疗效确切，尤其对于皮肤软组织感 染疗效明显，值得临床推广应用。 关键词 夫西地酸乳膏；耐甲氧西林金黄色葡萄球菌；局部感染 Analysis of Clinical Pharmacists Participating in the Treatment of 2 Cases of MRSA Local Infection with Fusidic Acid Cream LIN Yao ，QIANG Shuan-hu ，XUE Xiao-juan ，GAO Ya ，ZHAO Jie ，ZHANG Yao-feng ，WANG Xiao-juan （Dept. of Pharmacy ，Stomatological Hospital of Fourth Military Medical University ，Xi ’an 710032，China ） ABSTRACT OBJECTIVE ：To provide reference for MRSA local infection therapy. METHODS ：The clinical pharmacists partici- pated in therapy for 2 patients who were locally infected with MRSA. The therapy methods ，clinical effect and causes were ana- lyzed respectively. RESULTS ：2patients ，who were locally infected with MRSA ，did not have the systemic symptom and the con- ditions of antibiotics use. The suggestion provided by clinical pharmacists was local use of Fusidic acid cream. After the patients used Fusidic acid cream for 3to 5 days ，local symptom had been relieved significantly and the infection was controlled effectively. CONCLUSIONS ：Fusidic acid cream is effective in the treatment of MRSA local infection patients without systemic infection ，espe- cially for soft tissue infections. It is worthy of spreading in the clinic. KEYWORDS Fusidic acid cream ；MRSA ；Local infection 目前全世界范围内抗菌药物的滥用，使临床出现了大量耐 痛、溢脓症状，院外局部冲洗换药一段时间，效果不理想。入 药致病菌，尤其是耐甲氧西林金黄色葡萄球菌（MRSA ）对多种