Analysis of the Release Characteristics of Cu-Treated Antimicrobial Implant Surfaces Using Atomic Absorption Spectrometry英文文献资料.docVIP

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Analysis of the Release Characteristics of Cu-Treated Antimicrobial Implant Surfaces Using Atomic Absorption Spectrometry英文文献资料.doc

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Analysis of the Release Characteristics of Cu-Treated Antimicrobial Implant Surfaces Using Atomic Absorption Spectrometry英文文献资料

HindawiPublishingCorporation BioinorganicChemistryandApplications Volume2012,ArticleID850390,5pages doi:10.1155/2012/850390 ResearchArticle AnalysisoftheReleaseCharacteristicsof Cu-TreatedAntimicrobialImplantSurfacesUsing AtomicAbsorptionSpectrometry CarmenZietz, RainerHippler, 1 AndreasFritsche, 3 1 BirgitFinke, VitezslavStranak, MaximilianHaenle, 2 3 1 andRainerBader 1 WolframMittelmeier, 1 1 BiomechanicsandImplantTechnologyResearchLaboratory,DepartmentofOrhtopeadics,UniversityofRostock, DoberanerStraβe142,18057Rostock,Germany 2 3 LeibnizInstituteforPlasmaScienceandTechnology(INPe.V.Greifswald),Felix-Hausdor?-Straβe2,17489Greifswald,Germany InstituteofPhysics,Ernst-Moritz-ArndtUniversityofGreifswald,Felix-Hausdor?-Straβe6,17487Greifswald,Germany CorrespondenceshouldbeaddressedtoCarmenZietz,carmen.zietz@med.uni-rostock.de Received1September2011;Accepted24October2011 AcademicEditor:ReinhardPaschke Copyright?2012CarmenZietzetal.ThisisanopenaccessarticledistributedundertheCreativeCommonsAttributionLicense, whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperlycited. Newdevelopmentsofantimicrobialimplantsurfacesdopedwithcopper(Cu)ionsmayminimizetheriskofimplant-associated infections.However,experimentalevaluationoftheCureleaseisin?uencedbyvarioustestparameters.Theaimofourstudy wastoevaluatetheCureleasecharacteristicsinvitroaccordingtothestorage?uidandsurfaceroughness.Plasmaimmersion ionimplantationofCu(Cu-PIII)andpulsedmagnetronsputteringprocessofatitaniumcopper?lm(Ti-Cu)wereappliedto titaniumalloy(Ti6Al4V)sampleswithdi?erentsurface?nishingoftheimplantmaterial(polished,hydroxyapatiteandcorundum blasted).Thesamplesweresubmersedintoeitherdouble-distilledwater,humanserum,orcellculturemedium.Subsequently, theCuconcentrationinthesupernatantwasmeasuredusingatomicabsorptionspectrometry.Thetest?uidaswellasthesurface roughnesscanaltertheCureleasesigni?cantly,wherebythehighestCureleasewasde