Congenital sepsis caused by Eikenella corrodens英文文献资料.docVIP

Open Journal of Pediatrics, 2012, 2, 175-177 OJPed /10.4236/ojped.2012.22029 Published Online June 2012 (http://www.SciRP.org/journal/ojped/) Congenital sepsis caused by Eikenella corrodens Brittany L. Hu , Julie-Ann M. Crewalk , David P. Ascher 1 2 3 1 2 3 School of Medicine, University of Virginia, Charlottesville, USA Pediatric Infectious Disease Group, Inova Health System Hospital for Children, Fairfax, USA Department of Pediatrics, Inova Health System Hospital for Children, Fairfax, USA Email: jcrewalk@ Received 30 November 2011; revised 2 May 2012; accepted 11 May 2012 ABSTRACT of neonatal infections, E. corrodens remains a rare etiol- ogy of neonatal sepsis [5]. We searched the literature for reported cases of con- genital Eikenella sepsis with positive blood cultures at birth. We describe the fourth case. Eikenella corrodens is a part of normal human oral flora and a rare cause of intrauterine and neonatal infections. We describe a case of congenital E. cor- rodens sepsis with positive blood cultures at birth in the setting of low maternal risk factors for infection. Our case is one of two reported cases of congenital E. corrodens sepsis resulting in newborn survival. 2. CASE A 30 year-old woman, gravida II para I, was admitted at 33 weeks and 2 days gestation for preterm labor. On the day of delivery, the mother was afebrile, although she had an elevated white blood cell count of 19,900/mm3. The mother was otherwise healthy and had received pre- natal care throughout her pregnancy. Prenatal testing was negative for human immunodeficiency virus, hepatitis B virus, rubella, and syphilis. The mother denied periodon- tal disease or any history of a human bite. For a living, she trained German Shepherds, but denied any bites or wounds from the dogs. She also denied any oral-genital c