A Public Health Emergency of International Concern Response to a Proposal to Apply the International Health Regulations to Antimicrobial Resistance 英文参考文献.docVIP
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A Public Health Emergency of International Concern Response to a Proposal to Apply the International Health Regulations to Antimicrobial Resistance 英文参考文献
Perspective
APublicHealthEmergencyofInternationalConcern?
ResponsetoaProposaltoApplytheInternationalHealth
RegulationstoAntimicrobialResistance
AdamKamradt-Scott*
DepartmentofGlobalHealthDevelopment,LondonSchoolofHygieneTropicalMedicine,London,UnitedKingdom
Thereislittlequestionthattheinterna-
tional spread of antimicrobial resistance
(AMR) is an alarming development that
the global public health community must
confront as a matter of some priority.
Reducing the incidence of new cases will
taketheconcertedeffortandparticipation
ofallcommunitysectors,andwillrequire
strong political leadership. The World
of‘‘disease’’[4],buttheiressentialfunction
remained unchanged—they are a frame-
work to guide inter-state behaviour when
confronted with an acute public health
emergency that threatens to disrupt inter-
nationaltradeandtravel.
LinkedPolicyForum
This Perspective discusses the fol-
lowingnewPolicyForumpublished
inPLoSMedicine:
To emphasise this dual focus, the
revised IHR introduced the concept of a
PHEIC.AsdefinedinArticle1,aPHEIC
is an ‘‘extraordinary event’’ that consti-
tutesapublichealthrisk,whichmayalso
require a coordinated international re-
sponse. While outbreaks of carbapenem-
resistant Enterobacteriaceae (CRE) are a
worrying development that may warrant
reportingundertheIHR(andprovisionis
alreadymadeforthiswithinAnnex2),itis
hard to appreciate that the global spread
of AMR counts as ‘‘extraordinary’’ given
that resistance has been a regular phe-
nomenonsincetheinventionofantibiotics
inthe1940sandmultidrugAMRhasbeen
anticipated for at least the past three
WernliD,HausteinT,ConlyJ,Carmeli
Y,KickbuschI,etal.(2011)ACallfor
Action: The Application of the Inter-
national Health Regulations to the
Global Threat ofAntimicrobialResis-
tance. PLoS Med 8(4): e1001022.
doi:10.1371/journal.pmed.1001022
/article/
info:doi/10.1371/journal.pmed.1001022
Health
Organization (WHO) is best
placed to lead the international commu-
nity’s efforts to tackle this phenomenon,
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