MembraneProteinStructurePredictionandVisualization.pptVIP

Membrane ProteinStructure Prediction and Visualization Chuck Staben Jerzy Jaromczyk Genomic View Protein Structure Determination Bioinformatics-what is it? Acquisition, curation, and analysis of biological data Typical Cell ~10% proteins membrane bound Up to 90% cell’s energy involved in transport Receptors, transporters, adhesion Basic and applied Protein Structure Rasmol image 3D structure (tertiary) Secondary structure Alpha helix Beta sheet PRIMARY STRUCTURE ? 3D Structure Primary Structure 20 amino acids Unique chemical properties 100-1000’s (400 typical) Structure Prediction Quantum