ProteinSecondaryStructure.pptVIP

Protein Secondary Structure Lecture 2/19/2003 Three Dimensional Protein Structures The Amide bond Torsion angles Ramachandran plot Secondary structure can be defined by f and y angles Steric hindrance between the amide nitrogen and the carbonyl * Confirmation: Spatial arrangement of atoms that depend on bonds and bond rotations. Proteins can change conformation, however, most proteins have a stable “native” conformation. The native protein is folded through weak interactions: a) hydrophobic interaction b) Hydrogen bonds c) Ionic bonds d) Van der Waals attractions A Denatured protein is