African AIDS Vaccine Programme for a Coordinated and Collaborative Vaccine Development Effort on the Continent 英文参考文献.docVIP

Health In Action African AIDS Vaccine Programme for a Coordinated and Collaborative Vaccine Development Effort on the Continent Pontiano Kaleebu*, Alash’le Abimiku, Shenaaz El-Halabi, Sinata Koulla-Shiro, Nicole Mamotte, Souleymane Mboup, Roy Mugerwa, John Nkengasong, Coumba Toure-Kane, Tim Tucker, Douglas Wassenaar, Carolyn Williamson, Dawit Wolday N early 30 years after the first cases of AIDS were reported [1] and HIV identified as the Summary Points with candidate vaccines that were not based on strains circulating in Africa. AAVP was created with the specific intention of mobilizing support and advocating for a more Africa-focused vaccine agenda. In 2000, representative African scientists met in Nairobi to create AAVP and issued a declaration— “An African Appeal for an AIDS Vaccine” [5]. The mission of AAVP is to advocate for and support a coordinated international effort to promote the development of and future access to HIV vaccines suitable for sè 4HEè!)$3èPANDEMICèCONTINUESèTOè be the most serious public health challenge facing the world today, and Africa bears an overwhelming proportion of infections, with unprecedented medical and causative agent, Africa today bears a disproportionate burden of the disease. Sub-Saharan Africa has just over 10% of the world’s population but is home to more than 65% of the 33 million people in the world estimated to be living with HIV/AIDS. The annual rate of new infections continues to rise, with an estimated 2.5 million people newly infected in 2007 [2]. socioeconomic consequences. sè 4HEèBESTèHOPEèTOèENDèTHEè!)$3è pandemic remains the development of an effective HIV vaccine, and its distribution to all communities. Although newer initiatives aimed at providing universal access to sè 4HEè!FRICANè!)$3è6ACCINEè0ROGRAMMEè (AAVP), formed in 2000, is a network of African HIV vaccine stakeholders, led by Africans across the continent, with a vision of an African continent without AIDS. antiretroviral therapy in Africa are on