Age Differences in Intra-Individual Variability in Simple and Choice Reaction Time Systematic Review and Meta-Analysis 英文参考文献.docVIP

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Age Differences in Intra-Individual Variability in Simple and Choice Reaction Time Systematic Review and Meta-Analysis 英文参考文献.doc

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Age Differences in Intra-Individual Variability in Simple and Choice Reaction Time Systematic Review and Meta-Analysis 英文参考文献

AgeDifferencesinIntra-IndividualVariabilityinSimple andChoiceReactionTime:SystematicReviewandMeta- Analysis DominikaDykiert1*,GeoffDer1,2,JohnM.Starr3,IanJ.Deary1 1DepartmentofPsychology,CentreforCognitiveAgeingandCognitiveEpidemiology,UniversityofEdinburgh,Edinburgh,UnitedKingdom,2MedicalResearchCouncil Social and Public Health Sciences Unit, Glasgow, United Kingdom, 3Geriatric Medicine Unit, Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh,Edinburgh,UnitedKingdom Abstract Background: Intra-individual variability in reaction time (RT IIV) is considered to be an index of central nervous system functioning.Suchvariabilityiselevatedinneurodegenerativediseasesorfollowingtraumaticbraininjury.Ithasalsobeen suggestedtoincreasewithageinhealthyageing. Objectives:ToinvestigateandquantifyagedifferencesinRTIIVinhealthyageing;toexaminetheeffectofdifferenttasks andprocedures;tocomparerawandmean-adjustedmeasuresofRTIIV. DataSources:Fourelectronicdatabases:PsycINFO,Medline,WebofScienceandEMBASE,andhandsearchingofreference listsofrelevantstudies. Study Eligibility: English language journal articles, books or book chapters, containing quantitative empirical data on simpleand/orchoiceRTIIV.Sampleshadtoincludeyounger(under60years)andolder(60yearsandabove)humanadults. StudyAppraisalandSynthesis:Studieswereevaluatedintermsofsamplerepresentativenessanddatatreatment.Relevant datawereextracted,usingaspecially-designedform,fromthepublishedreportorobtaineddirectlyfromthestudyauthors. Age-groupdifferencesinrawandRT-mean-adjustedmeasuresofsimpleandchoiceRTIIVwerequantifiedusingrandom effectsmeta-analyses. Results:Olderadults(60+years)hadgreaterRTIIVthanyounger(20–39)andmiddle-aged(40–59)adults.Ageeffectswere largerinchoice RTtasks thanin simpleRT tasks.For allmeasuresofRT IIV, effectsizeswerelargerfor thecomparisons betweenolderandyoungeradultsthanbetweenolderandmiddle-agedadults,indicatingthattheage-relatedincreasesin RTIIVarenotlimitedtooldage.Effectsizes