尿素与甘油反应制甘油碳酸酯的绿色合成工艺.pdfVIP

学兔兔 化 工 进 展 CHEMICAL INDUSTRY AND ENGINEERING PROGRESS 2012年第3 1卷第3期 尿素与甘油反应制甘油碳酸酯的绿色合成工艺 郭 爽，李金丽，王家喜 (河北工业大学化工学院，天津 300130) 摘 要：以甘油和尿素为原料，探讨了低甘油含量的甘油碳酸酯环境友好的合成工艺 考察了催化剂的结构、 反应条件等因素对甘油转化率的影响，结果表明在390℃煅烧3 h的硫酸锌催化效果最好。采用甘油与尿素反 应后再与碳酸酯反应的偶合反应方式，所得甘油碳酸酯中甘油的含量仅为0 6％，降低了合成成本。 关键词：甘油碳酸酯；尿素；硫酸锌；甘油的利用 中图分类号：TQ 225．52 文献标志码：A 文章编号：1000—6613(2012)03—0658—05 Investigation on a green synthetic approach for glycerol carbonate： The reaction of glycerol with urea GUO Shuang，LIJinli，WANGJiaxi (School ofChemical Engineering，Hebei University ofTechnology，Tianjin 300130，China) Abstract：An environmentally friendly synthesis approach of glycerol carbonate with low glycerol residue was evaluated by using glycerol and urea as raw materials．The effects of catalyst structure and reaction condition on the conversion of glycerol were investigated．The results showed that the zinc sulfate calcined at 390℃ for 3 h had the highest activity．The glycerol content in product can be reduced by the combination of batch reaction of glycerol with urea and then with dimethylcarbonate， by which the glycerol content in the glycerol carbonate iS lower to 0．6％，and the synthesis cost of glycerol carbonate is reduced as wel1． Key words：glycerol carbonate；urea；zinc sulfate；utilization of glycerol 甘油碳酸酯是一种稳定的、低毒性、低挥发性、 油转化率可达62％～65％，选择性接近92％。褚昭 低可燃性、具有吸水性的无色液体，广泛应用于化 宁 0]研究了催化剂的种类对甘油与尿素的反应的 妆品领域和医学配置剂的溶剂载体及添加剂…。此 影响，结果表明具有Lewis酸性的硫酸盐催化活 外，甘油碳酸酯的高反应活性，可作为有机合成 性