Differential GoNoGo Activity in Both Contingent Negative Variation and Spectral Power 英文参考文献.docVIP
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Differential GoNoGo Activity in Both Contingent Negative Variation and Spectral Power 英文参考文献
DifferentialGo/NoGoActivityinBothContingent
NegativeVariationandSpectralPower
IngridFunderud1*,MagnusLindgren1,2,MarianneL?vstad3,TorEndestad1,4,BradleyVoytek5,6
,
RobertT.Knight6,7,Anne-KristinSolbakk1
1Department of Neuropsychiatry and PsychosomaticMedicine, Division ofSurgery and Clinical Neuroscience,Oslo University Hospital- Rikshospitalet, Oslo, Norway,
2DepartmentofPsychology,LundUniversity,Lund,Sweden,3SunnaasRehabilitationHospital,Nesodden,Norway,4DepartmentofPsychology,UniversityofOslo,Oslo,
Norway, 5Department of Neurology, University of California San Francisco, San Francisco, California, United States of America, 6Helen Wills Neuroscience Institute,
UniversityofCalifornia,Berkeley,California,UnitedStatesofAmerica,7DepartmentofPsychology,UniversityofCalifornia,Berkeley,California,UnitedStatesofAmerica
Abstract
We investigated whether both the contingent negative variation (CNV), an event-related potential index of preparatory
brainactivity,andevent-relatedoscillatoryEEGactivitydifferentiatedGoandNoGotrialsinadelayedresponsetask.CNV
andspectralpower(4–100Hz)werecalculatedfromEEGactivityinthepreparatoryintervalin16healthyadultparticipants.
As previously reported, CNV amplitudes were higher in Go compared to NoGo trials. In addition, event-related spectral
poweroftheGoconditionwasreducedinthethetatolowgammarangecomparedtotheNoGocondition,confirmingthat
preparingtorespondisassociatedwithmodulationofevent-relatedspectralactivityaswellastheCNV.Altogether,the
impact of the experimental manipulation on both slow event-related potentials and oscillatory EEG activity may reflect
coordinateddynamicchangesintheexcitabilityofdistributedneuralnetworksinvolvedinpreparation.
Citation:FunderudI,LindgrenM,L?vstadM,EndestadT,VoytekB,etal.(2012)DifferentialGo/NoGoActivityinBothContingentNegativeVariationandSpectral
Power.PLoSONE7(10):e48504.doi:10.1371/journal.pone.0048504
Editor:LawrenceM.Ward,UniversityofBritishColumbia,Canada
ReceivedJuly4,2012;AcceptedSeptember26,2012;P
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