Effect of Diuretic Use on 30-Day Postdialysis Mortality in Critically Ill Patients Receiving Acute Dialysis 英文参考文献.docVIP

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Effect of Diuretic Use on 30-Day Postdialysis Mortality in Critically Ill Patients Receiving Acute Dialysis 英文参考文献.doc

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Effect of Diuretic Use on 30-Day Postdialysis Mortality in Critically Ill Patients Receiving Acute Dialysis 英文参考文献

EffectofDiureticUseon30-DayPostdialysisMortalityin CriticallyIllPatientsReceivingAcuteDialysis Vin-CentWu1,9.,Chun-FuLai1.,Chih-ChungShiao2,Yu-FengLin3,Pei-ChenWu1,Chia-TerChao1 ,Fu- ChangHu5,Tao-MinHuang6,Yu-ChangYeh7,I-JungTsai8,Tze-WahKao1,Yin-YiHan3,Wen-ChungWu10, Chun-ChengHou11,Guang-HuarYoung3,Wen-JeKo3,4*,Tun-JunTsai1,Kwan-DunWu1 1Division of Nephrology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan, 2Division of Nephrology, Department of Internal Medicine,SaintMary’sHospital,andSaintMary’sMedicine,NursingandManagementCollege,Yilan,Taiwan,3DepartmentofTraumatology,NationalTaiwanUniversity Hospital, Taipei, Taiwan, 4Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan, 5International Harvard Statistical Consulting Company, Taipei, Taiwan, 6Division of Nephrology, Department of Internal Medicine, Yun-Lin Branch, Douliou City, Yun-Lin County, Taiwan, 7Department of Anesthesiology, National TaiwanUniversityHospital,Taipei,Taiwan,8DepartmentofPediatrics,NationalTaiwanUniversityHospital,Taipei,Taiwan,9NSARF:NationalTaiwanUniversityHospital StudyGrouponAcuteRenalFailure,Taipei,Taiwan,10SectionofInternalMedicine,Miao-LiHospital,DepartmentofHealth,Miao-Li,Taiwan,11DepartmentofInternal medicine,Min-ShengHospital,Tao-Yuan,Taiwan Abstract Background:Theimpactofdiureticusageanddosageonthemortalityofcriticallyillpatientswithacutekidneyinjuryisstill unclear. Methods and Results: In this prospective, multicenter, observational study, 572 patients with postsurgical acute kidney injuryreceivinghemodialysiswererecruitedandfolloweddaily.Thirty-daypostdialysismortalitywasanalyzedusingCox’s proportional hazards model with time-dependent covariates. The mean age of the 572 patients was 60.8616.6 years. Patients with lower serum creatinine (p=0.031) and blood lactate (p=0.033) at ICU admission, lower predialysis urine output(p=0.001)andPaO2/FiO2(p=0.039),aswellasdiabetes(p=0.037)andheartfailure(p=0.049)weremorelikelyto