Genome-Wide Assessment for Genetic Variants Associated with Ventricular Dysfunction after Primary Coronary Artery Bypass Graft Surgery 英文参考文献.docVIP

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Genome-Wide Assessment for Genetic Variants Associated with Ventricular Dysfunction after Primary Coronary Artery Bypass Graft Surgery 英文参考文献.doc

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Genome-Wide Assessment for Genetic Variants Associated with Ventricular Dysfunction after Primary Coronary Artery Bypass Graft Surgery 英文参考文献

Genome-WideAssessmentforGeneticVariants AssociatedwithVentricularDysfunctionafterPrimary CoronaryArteryBypassGraftSurgery AmandaA.Fox1*,MiasPretorius2,Kuang-YuLiu1,CharlesD.Collard3,TjorviE.Perry4,StantonK. Shernan1,PhilipL.DeJager5,DavidA.Hafler6,DanielS.Herman7,StevenR.DePalma7,DanM.Roden8, JochenD.Muehlschlegel1,BrianS.Donahue2,DawoodDarbar9,J.G.Seidman7,SimonC.Body1, ChristineE.Seidman7,10,11 1Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, 2Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of Ameica, 3Division of Cardiovascular AnesthesiaattheTexasHeartInstitute,SaintLuke’sEpiscopalHospital,Houston,Texas,UnitedStatesofAmerica,4NorthwestAnesthesiaPA,Minneapolis,Minnesota, United States of America, 5Department of Neurology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, 6DepartmentofNeurology,YaleSchoolofMedicine,NewHaven,Connecticut,UnitedStatesofAmerica,7DepartmentofGeneticsandPartnersHealthCareCenterfor GeneticsandGenomics,HarvardMedicalSchool,Boston,Massachusetts,UnitedStatesofAmerica,8DepartmentsofMedicineandPharmacology,VanderbiltUniversity SchoolofMedicine,Nashville,Tennessee,UnitedStatesofAmerica, 9DepartmentofMedicine,VanderbiltUniversitySchoolofMedicine,Nashville,Tennessee,United States of America, 10Division of Cardiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, 11Howard HughesMedicalInstitute,Boston,Massachusetts,UnitedStatesofAmerica Abstract Background:Postoperativeventriculardysfunction(VnD)occursin9–20%ofcoronaryarterybypassgraft(CABG)surgical patients and is associated with increased postoperative morbidity and mortality. Understanding genetic causes of postoperativeVnDshouldenhancepatientriskstratificationandimprovetreatmentandpreventionstrategies.We