Large-Scale Sequence Analysis of Hemagglutinin of Influenza A Virus Identifies Conserved Regions Suitable for Targeting an Anti-Viral Response 英文参考文献.docVIP
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Large-Scale Sequence Analysis of Hemagglutinin of Influenza A Virus Identifies Conserved Regions Suitable for Targeting an Anti-Viral Response 英文参考文献
Large-ScaleSequenceAnalysisofHemagglutininof
InfluenzaAVirusIdentifiesConservedRegionsSuitable
forTargetinganAnti-ViralResponse
LeepakshiSahini1,AnnaTempczyk-Russell2,RituAgarwal1*
1DepartmentofProcessandAnalyticalBiochemistry,ChimericBioIncorporated,LongIslandCity,NewYork,UnitedStatesofAmerica,2DepartmentofComputational
BiologyandChemistry,AccelrysIncorporated,SanDiego,California,UnitedStatesofAmerica
Abstract
Background: Influenza A viral surface protein, hemagglutinin, is the major target of neutralizing antibody response and
henceamainconstituent ofallvaccineformulations.Butduetoitsmark
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