Late Replicating Domains Are Highly Recombining in Females but Have Low Male Recombination Rates Implications for Isochore Evolution 英文参考文献.docVIP

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Late Replicating Domains Are Highly Recombining in Females but Have Low Male Recombination Rates Implications for Isochore Evolution 英文参考文献.doc

Late Replicating Domains Are Highly Recombining in Females but Have Low Male Recombination Rates Implications for Isochore Evolution 英文参考文献

LateReplicatingDomainsAreHighlyRecombiningin FemalesbutHaveLowMaleRecombinationRates: ImplicationsforIsochoreEvolution CatherineJ.Pink,LaurenceD.Hurst* DepartmentofBiologyandBiochemistry,UniversityofBath,Bath,UnitedKingdom Abstract In mammals sequences that are either late replicating or highly recombining have high rates of evolution at putatively neutralsites.AsearlyreplicatingdomainsandhighlyrecombiningdomainsbothtendtobeGCrichweaprioriexpectthese twovariablestocovary.Ifso,therelativecontributionofeitherofthesevariablestothelocalneutralsubstitutionratemight have been wrongly estimated owi

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