Pumpless extracorporeal interventional lung assist in patients with acute respiratory distress syndrome a prospective pilot study 英文参考文献.docVIP

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Pumpless extracorporeal interventional lung assist in patients with acute respiratory distress syndrome a prospective pilot study 英文参考文献.doc

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Pumpless extracorporeal interventional lung assist in patients with acute respiratory distress syndrome a prospective pilot study 英文参考文献

Available online /content/13/1/R10 Research Open Access Vol 13 No 1 Pumpless extracorporeal interventional lung assist in patients with acute respiratory distress syndrome: a prospective pilot study Markus Zimmermann1, Thomas Bein1, Matthias Arlt1, Alois Philipp2, Leopold Rupprecht2, Thomas Mueller3, Matthias Lubnow3, Bernhard M Graf1 and Hans J Schlitt4 1Department of Anesthesiology, University of Regensburg Medical Center, Franz-Josef-Strau?-Allee 11, Regensburg, 93053, Germany 2Department of Cardiothoracic and Vascular Surgery, University of Regensburg Medical Center, Franz-Josef-Strau?-Allee 11, Regensburg, 93053, Germany 3Department of Internal Medicine II, University of Regensburg Medical Center, Franz-Josef-Strau?-Allee 11, Regensburg, 93053, Germany 4Department of General Surgery, University of Regensburg Medical Center, Franz-Josef-Strau?-Allee 11, Regensburg, 93053, Germany Corresponding author: Markus Zimmermann, markus.zimmermann@klinik.uni-regensburg.de Received: 2 Sep 2008 Revisions requested: 20 Oct 2008 Revisions received: 23 Dec 2008 Accepted: 30 Jan 2009 Published: 30 Jan 2009 Critical Care 2009, 13:R10 (doi:10.1186/cc7703) This article is online at: /content/13/1/R10 ? 2009 Zimmermann et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction Pumpless interventional lung assist (iLA) is used in patients with acute respiratory distress syndrome (ARDS) aimed at improving extracorporeal gas exchange with a membrane integrated in a passive arteriovenous shunt. In previous studies, feasibility and safety of the iLA system was demonstrated, but no survival benefit was observed. In the present pilot study we tested the hypothesis that timely initiation of iLA using clear algorithms and