Recurrent Pleural and Pericardial Effusions Due to Sarcoidosis 英文参考文献.docVIP

o Openaccess,freelyavailableonline PL S MEDICINE CaseReport RecurrentPleuralandPericardialEffusions DuetoSarcoidosis Sankar D.Navaneethan*,Sundar Venkatesh, Rakesh Shrivastava, Jagat Mehta, Robert Israel CasereportfromDepartmentofInternalMedicine,UnityHealthSystem,Rochester,NewYork,UnitedStatesofAmerica CompetingInterests:Theauthors havedeclaredthatnocompeting interestsexist. PRESENTATIONofCASE relieving his symptoms, and he was dis- charged. A During his third (current) admission, labo- ratory investigations were unremarkable. Repeat CT scan of the chest showed a left- sided pleural effusion, normal lung paren- chyma, a small pericardial effusion, and mediastinal lymph nodes (Figure 1). Video- assisted thoracoscopic pleural biopsy showed nonspecific chronic inflammation. Mediastinal lymph node biopsy showed benign reactive lymph nodes with focal epithelioid, non-caseating granulomas con- sistent with sarcoidosis. The patient was treated with oral prednisone, 20 mg daily. Heremainedasymptomaticwhenseenathis 1-yfollow-up,whenhewastaking7.5mgof prednisonedaily. 54-y-old white male presented to the hospital during the winter of 2002withcomplaintsoffever,short- AuthorContributions:SV,RS,and JMcaredforthepatient.SDN,SV, andRIwrotethemanuscript. ness of breath, and left-sided pleuritic chest pain of 2 d duration. He was a nonsmoker without any significant family history of pulmonary disease. He was retired, and denied any past exposure to chemicals includingberyllium.Onphysicalexamination, thepatientwasfebrilewithtachycardiaand normalbloodpressure.Airentryatbothlung bases was diminished. The remainder of his history and physical examination was unre- markable. Citation:NavaneethanSD,Venka- teshS,ShrivastavaR,MehtaJ, IsraelR(2005)Recurrentpleural andpericardialeffusionsdueto sarcoidosis.PLoSMed2(3):e63. Received:November24,2004 Accepted:January20,2005 Published:March29,2005 DOI: 10.1371/journal.pmed.0020063 Copyright:ó2005Navaneethanet al.Thisisanopen-acce