Serum proteins and paraproteins in women with silicone implants and connective tissue disease a case–control study 英文参考文献.docVIP

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Serum proteins and paraproteins in women with silicone implants and connective tissue disease a case–control study 英文参考文献.doc

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Serum proteins and paraproteins in women with silicone implants and connective tissue disease a case–control study 英文参考文献

Available online /content/9/5/R95 Research article Open Access Vol 9 No 5 Serum proteins and paraproteins in women with silicone implants and connective tissue disease: a case–control study Gyorgy Csako1, Rene Costello1, Ejaz A Shamim2, Terrance P OHanlon2, Anthony Tran1,3, Daniel J Clauw4, H James Williams5 and Frederick W Miller2 1Department of Laboratory Medicine, Clinical Center, NIH, DHHS, 9000 Rockville Pike, Bethesda, MD 20892, USA 2Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, NIH, DHHS, 9000 Rockville Pike, Bethesda, MD 20892, USA 3Association of Public Health Laboratories, 8515 Georgia Avenue, Suite 700, Silver Spring, MD 20910, USA 4Division of Rheumatology, Department of Medicine, University of Michigan Medical School, 101 Simpson Drive, Ann Arbor, MI 48109, USA 5Division of Rheumatology, Department of Internal Medicine, University of Utah Medical Center, 50 North Medical Drive, Salt Lake City, UT 84132, USA Corresponding author: Gyorgy Csako, gcsako@ Received: 30 Apr 2007 Revisions requested: 19 Jun 2007 Revisions received: 9 Aug 2007 Accepted: 17 Sep 2007 Published: 17 Sep 2007 Arthritis Research Therapy 2007, 9:R95 (doi:10.1186/ar2295) This article is online at: /content/9/5/R95 ? 2007 Csako et al., licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Prior studies have suggested abnormalities of serum proteins, including paraproteins, in women with silicone implants but did not control for the presence of connective-tissue disease (CTD). This retrospective case–control study, performed in tertiary-care academic centers, assessed possible alterations of serum proteins, including paraproteins, in such a population. Seventy- four women with silicone implants wh