Severe respiratory distress in term infants born electively at high altitude 英文参考文献.docVIP

BMC Pregnancy and Childbirth BioMedCentral Research article Open Access Severe respiratory distress in term infants born electively at high altitude Ahmad F Bakr*1,3,4 and Mohammad M Abbas2 Address: 1Departments of Pediatrics, University of Alexandria, Alexandria, Egypt, 2Departments of Obstetrics, King Abdul-Aziz Specialist Hospital, Taif, Saudi Arabia, 3Consultant Neonatologist, Welcare Hospital, PO Box 31500 Dubai, United Arab Emirates and 4Obstetrics and Gynecology, Faculty of Medicine, University of Alexandria, Egypt Email: Ahmad F Bakr* - afb1963@; Mohammad M Abbas - mmabbas@ * Corresponding author Published: 16 February 2006 Received: 04 August 2005 Accepted: 16 February 2006 BMC Pregnancy and Childbirth 2006, 6:4 doi:10.1186/1471-2393-6-4 This article is available from: /1471-2393/6/4 ? 2006 Bakr and Abbas; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: We studied the contribution of elective delivery to severe respiratory distress syndrome (RDS) in term babies born at high altitude. Methods: We prospectively studied the charts of term babies born in Taif Maternity Hospital (1640 m above sea level) between 1/1/2004 and 31/10/2004 who developed RDS and required mechanical ventilation. Results: 8634 deliveries occurred from 37–41 weeks; 13 (0.15%) had RDS requiring mechanical ventilation. Seven infants delivered at 37–38 weeks, (OR for RDS = 26 95%CI -4.6 to 5.8), five delivered at 38–39 weeks, (OR for RDS = 10 95%CI -4.9 to 5.4) and one delivered at 39 weeks. Six of 13 infants were electively delivered without documented lung maturity. Conclusion: Infants born at 37 and 38 weeks gestation remain at significantly increased risk for severe RDS. Elective deliver