Setting Research Priorities To Reduce Global Mortality from Childhood Diarrhoea by 2015 英文参考文献.docVIP

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Setting Research Priorities To Reduce Global Mortality from Childhood Diarrhoea by 2015 英文参考文献.doc

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Setting Research Priorities To Reduce Global Mortality from Childhood Diarrhoea by 2015 英文参考文献

Guidelines and Guidance Setting Research Priorities To Reduce Global Mortality from Childhood Diarrhoea by 2015 Olivier Fontaine*, Margaret Kosek, Shinjini Bhatnagar, Cynthia Boschi-Pinto, Kit Yee Chan, Christopher Duggan, Homero Martinez, Hugo Ribeiro, Nigel C. Rollins, Mohammed A. Salam, Mathuram Santosham, John D. Snyder, Alexander C. Tsai, Beth Vargas, Igor Rudan C hildhood diarrhoea still claims nearly 2 million lives each year and remains responsible for 18% of all child deaths [1,2]. Regardless of this, research in different research options, and (iii) the likelihood of achieving reductions of persisting burden of disease and disability through investments. The CHNRI methodology has three stages: input from investors and policy makers (defining the context and criteria for priority setting); input from technical experts (listing and scoring research investment options); and input from other stakeholders (weighing the criteria according to wider societal system of values) [10–12]. The aim of this particular implementation of the CHNRI method was to inform key global donors, investors in health research (especially of public funds), and international agencies on research investment policies that are expected to interest in this disease has been steadily decreasing after the development of cost-effective interventions in the 1980s [3]. In addition, the amount of available research funds per disability-adjusted life year (DALY) are several orders of magnitude lower for diarrhoea when compared to some other diseases, such as autism or diabetes type 2 [4]. The UN’s Millennium Development Goal #4 (MDG4) states that childhood mortality should be reduced by two thirds between 1990 and 2015 [5], but recent estimates show that the progress in mortality reduction has not accelerated in comparison to 30 years ago [2]. Therefore this MDG target is likely to be missed. However, the reduction of child deaths by two thirds could be achieved by 2015 if presently available cost