Serum procalcitonin level and leukocyte antisedimentation rate as early predictors of respiratory dysfunction after oesophageal tumour resection 英文参考文献.docVIP

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Serum procalcitonin level and leukocyte antisedimentation rate as early predictors of respiratory dysfunction after oesophageal tumour resection 英文参考文献.doc

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Serum procalcitonin level and leukocyte antisedimentation rate as early predictors of respiratory dysfunction after oesophageal tumour resection 英文参考文献

Available online /content/10/4/R110 Research Open Access Vol 10 No 4 Serum procalcitonin level and leukocyte antisedimentation rate as early predictors of respiratory dysfunction after oesophageal tumour resection Lajos Bogar, Zsolt Molnar, Piroska Tarsoly, Peter Kenyeres and Sandor Marton Department of Anaesthesiology and Intensive Care, University of Pecs, Hungary Corresponding author: Lajos Bogar, bogar@clinics.pote.hu Received: 1 Mar 2006 Revisions requested: 24 Apr 2006 Revisions received: 16 May 2006 Accepted: 17 Jul 2006 Published: 19 Jul 2006 Critical Care 2006, 10:R110 (doi:10.1186/cc4992) This article is online at: /content/10/4/R110 ? 2006 Bogar et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction Postoperative care after oesophageal tumour resection holds a high risk of respiratory complications. We therefore aimed to determine the value of systemic inflammatory markers in predicting arterial hypoxaemia as the earliest sign of developing lung injury after oesophageal tumour resection. Results Seventeen out of 33 patients were classified as hypoxaemic and 16 patients as normoxaemic at T3. Increases of temperature at T0 and of the procalcitonin and LAR values at T2 were predictive of hypoxaemia at T3 (P 0.05, P 0.01 and P 0.001, respectively). The area under the receiver-operating characteristic curve was 0.65 for the temperature at T0, which was significantly lower than that for the procalcitonin level at T2 (0.83; 95% confidence interval, 0.69–0.97; P 0.01) and that for LAR at T2 (0.89; 95% confidence interval, 0.77–1.00; P 0.001). Methods In a prospective observational study, 33 consecutive patients were observed for three days (T1–T3) after admission (T0