Survey of recent situation of chromosome pathology in different breeds of german cattle 英文参考文献.docVIP

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Survey of recent situation of chromosome pathology in different breeds of german cattle 英文参考文献.doc

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Survey of recent situation of chromosome pathology in different breeds of german cattle 英文参考文献

y asse oz A. HERZOG, Henni H?HN G. .p Institut für Zuchthygiene und Vetevinavmedizinische Genetik 3 oo Giessen (Bundesre With the aim to elucidate the etiological role of chromosome anomalies in pathology of domestic animals karyotype analyses had beenperformed routinically in congenital malformations, furthermore in adult cattle with hereditary diseases, andin individuals with malformations of genital organs. The investigations have been realized during the 10 years within the three large breeds of the cattle population of Hessen. malies of different types have been found 2. Considering the impossibility in karyotyping all calves with congenital anomalies exten- and in regard of the of a impractibility cytogenetic explo- ration of whole the population, it seems to be impossible to derive more than rough estimations of the real frequencies of chromosome anomalies within the observed population. 3. The first rank of different types of chromosome anomalies is occupied by the z / trans- 1 is not taken in consideration because its frequency is depending exclusively from the frequencies of heterozygous twins within the different breeds). Considering their real frequencies both types of chromosome anomalies dont possess a noteworthy economical importance within the observed population in the present situation. All other chromosomal anomalies, especially autosomal structural defects, too, are found only sporadically, though accumulated in certain families. This is the case in bovine hereditary parakeratosis, and in hereditary nanism. 81 4. The occurrence of several probands with the trisomy syndrome (lethal brachygnathia trisomy syndrome) in a family together with gonosomal numerical anomalies is estimated to be the expression of a familiar disposition to disturbances of meiosis, resp. mitosis. of bovine hereditary parakeratosis the symptomatology of those, by chromosome anomalies caused, resp. with chromosome anomalies combined,