Synthesis and evaluation of 2-chloro N-[(S)-{(S)-1-[11?C]methylpiperidin-2-yl} (phenyl)methyl]3-trifluoromethyl-benzamide ([11?C]N-methyl-SSR504734) as a PET radioligand for glycine transporter 1 英文参考文献.docVIP

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Synthesis and evaluation of 2-chloro N-[(S)-{(S)-1-[11?C]methylpiperidin-2-yl} (phenyl)methyl]3-trifluoromethyl-benzamide ([11?C]N-methyl-SSR504734) as a PET radioligand for glycine transporter 1 英文参考文献.doc

Synthesis and evaluation of 2-chloro N-[(S)-{(S)-1-[11?C]methylpiperidin-2-yl} (phenyl)methyl]3-trifluoromethyl-benzamide ([11?C]N-methyl-SSR504734) as a PET radioligand for glycine transporter 1 英文参考文献

Fuchigamietal.EJNMMIResearch2012,2:37 /content/2/1/37 ORIGINAL RESEARCH OpenAccess Synthesisandevaluationof2-chloro 11 N-[(S)-{(S)-1-[ C]methylpiperidin-2-yl} (phenyl)methyl]3-trifluoromethyl-benzamide 11 ([ C]N-methyl-SSR504734)asaPETradioligand forglycinetransporter1 TakeshiFuchigami1,2,AkihiroTakano3*,BalázsGulyás3,ZhishengJia3,SjoerdJFinnema3,JanDAndersson3, RyujiNakao3,YasuhiroMagata2,MamoruHaratake1,MorioNakayama1andChristerHalldin3 Abstract Background:Dysfunctionoftheglycinetransporter1(GlyT1)hasbeensuggestedtobeinvolvedinpsychiatric disorderssuchasschizophrenia.GlyT1inhibitorshaveth

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