Synthesis of D-Homo Analogs of Neurosteroids 英文参考文献.docVIP

447 Molecules 2000, 5 Synthesis of D-Homo Analogs of Neurosteroids P. Di Chenna, A. A. Ghini and G. Burton Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellón 2, Ciudad Universitaria, (1428) Buenos Aires, Argentina E-mail: burton@qo.fcen.uba.ar Abstract: 17(13→18)-Abeo and D-homo analogs of the natural neurosteroid 3α-hydroxy- 5αH-pregnan-20-one were prepared by anionic or radical (mercury (II) hydride mediated) rearrangements of steroidal cyclopropylketones respectively. Introduction Certain steroids show an inhibitory