Systematic mapping of two component response regulators to gene targets in a model sulfate reducing bacterium 英文参考文献.docVIP

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Systematic mapping of two component response regulators to gene targets in a model sulfate reducing bacterium 英文参考文献.doc

Rajeevetal.GenomeBiology2011,12:R99 /2011/12/10/R99 RESEARCH OpenAccess Systematicmappingoftwocomponentresponse regulatorstogenetargetsinamodelsulfate reducingbacterium LaraRajeev,EricGLuning,ParamvirSDehal,MorganNPrice,AdamPArkinandAindrilaMukhopadhyay* Abstract Background:Twocomponentregulatorysystemsaretheprimaryformofsignaltransductioninbacteria.Although genomicbindingsiteshavebeendeterminedforseveraleukaryoticandbacterialtranscriptionfactors, comprehensiveidentificationofgenetargetsoftwocomponentresponseregulatorsremainschallengingdueto thelackofknowledgeofthesignalsrequiredfortheiracti

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