Systematic mapping of two component response regulators to gene targets in a model sulfate reducing bacterium 英文参考文献.docVIP
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Rajeevetal.GenomeBiology2011,12:R99
/2011/12/10/R99
RESEARCH
OpenAccess
Systematicmappingoftwocomponentresponse
regulatorstogenetargetsinamodelsulfate
reducingbacterium
LaraRajeev,EricGLuning,ParamvirSDehal,MorganNPrice,AdamPArkinandAindrilaMukhopadhyay*
Abstract
Background:Twocomponentregulatorysystemsaretheprimaryformofsignaltransductioninbacteria.Although
genomicbindingsiteshavebeendeterminedforseveraleukaryoticandbacterialtranscriptionfactors,
comprehensiveidentificationofgenetargetsoftwocomponentresponseregulatorsremainschallengingdueto
thelackofknowledgeofthesignalsrequiredfortheiracti
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