Targeting AMP-activated protein kinase in adipocytes to modulate obesity-related adipokine production associated with insulin resistance and breast cancer cell proliferation 英文参考文献.docVIP
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Targeting AMP-activated protein kinase in adipocytes to modulate obesity-related adipokine production associated with insulin resistance and breast cancer cell proliferation 英文参考文献
Grisouardetal.DiabetologyMetabolicSyndrome2011,3:16
/content/3/1/16
DIABETOLOGY
METABOLIC SYNDROME
SHORT REPORT
OpenAccess
TargetingAMP-activatedproteinkinasein
adipocytestomodulateobesity-relatedadipokine
productionassociatedwithinsulinresistanceand
breastcancercellproliferation
JeanGrisouard1*,KaethiDembinski1,DorisMayer2,UlrichKeller1,3,BeatMüller4andMirjamChrist-Crain1,3
Abstract
Background:Adipokines,e.g.TNFa,IL-6andleptinincreaseinsulinresistance,andconsequenthyperinsulinaemia
influencesbreastcancerprogression.Besideitsmitogeniceffects,insulinmayinfluenceadipokineproductionfrom
adipo
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