The clinical implications of adult-onset henoch-schonelin purpura 英文参考文献.docVIP

Jithpratucketal.ClinicalandMolecularAllergy2011,9:9 /content/9/1/9 CMA REVIEW OpenAccess Theclinicalimplicationsofadult-onset henoch-schonelinpurpura WaritJithpratuck1,YasminElshenawy2,HanaSaleh1,GeorgeYoungberg2,DavidSChi1andGuhaKrishnaswamy1,3* Abstract Henoch-SchonleinPurpura(HSP)isasmallvesselvasculitismediatedbyIgA-immunecomplexdeposition.Itis characterizedbytheclinicaltetradofnon-thrombocytopenicpalpablepurpura,abdominalpain,arthritisandrenal involvement.Pathologically,itcanbeconsideredaformofimmunecomplex-mediatedleukocytoclasticvasculitis (LCV)involvingtheskinandotherorgans.Thoughitp