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The clinical use of biomarkers as prognostic factors in Ewing sarcoma 英文参考文献
vanMaldegemetal.ClinicalSarcomaResearch2012,2:7
/content/2/1/7
CLINICAL SARCOMA RESEARCH
SHORT REPORT
OpenAccess
Theclinicaluseofbiomarkersasprognostic
factorsinEwingsarcoma
AnnmeikMvanMaldegem1,PancrasCWHogendoorn3andAndrewBHassan1,2*
Abstract
EwingSarcomaisthesecondmostcommonprimarybonesarcomawith900newdiagnosesperyearinEurope
(EU27).Ithasapoorsurvivalrateinthefaceofmetastaticdisease,withnomorethan10%survivalofthe35%
whodeveloprecurrence.Despitetheremainingmajorityhavinglocaliseddisease,approximately30%stillrelapse
anddiedespitesalvagetherapies.Prognosticfactorsmayidentifypatientsathigherr
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