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The complete linkage disequilibrium test a test that points to causative mutations underlying quantitative traits 英文参考文献
UlebergandMeuwissenGeneticsSelectionEvolution2011,43:20
/content/43/1/20
G
enetics
Selection
Evolution
RESEARCH
OpenAccess
Thecompletelinkagedisequilibriumtest:atest
thatpointstocausativemutationsunderlying
quantitativetraits
EivindUleberg1,2* andTheoHEMeuwissen1
Abstract
Background:Genetically,SNPthatareincompletelinkagedisequilibriumwiththecausativeSNPcannotbe
distinguishedfromthecausativeSNP.TheCompleteLinkageDisequilibrium(CLD)testpresentedheretests
whetheraSNPisincompleteLDwiththecausativemutationornot.TheperformanceoftheCLDtestis
evaluatedin1000simulateddatasets.
Methods:TheCLDtestcons
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