原创力文档The CRIT framework for identifying cross patterns in systems biology and application to chemogenomics 英文参考文献.docVIP
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The CRIT framework for identifying cross patterns in systems biology and application to chemogenomics 英文参考文献
Gianoulisetal.GenomeBiology2011,12:R32
/2011/12/3/R32
METHOD
OpenAccess
TheCRITframeworkforidentifyingcrosspatterns
insystemsbiologyandapplicationto
chemogenomics
TaraAGianoulis1,2,AshishAgarwal3,4,MichaelSnyder5andMarkBGerstein3,4,6*
Abstract
Biologicaldataisoftentabularbutfindingstatisticallyvalidconnectionsbetweenentitiesinasequenceoftables
canbeproblematic-forexample,connectingparticularentitiesinadrugpropertytabletogenepropertiesina
secondtable,usingathirdtableassociatinggeneswithdrugs.Herewepresentanapproach(CRIT)tofind
connectionssuchastheseandshowhowitcanbeappliedinavarietyofgenomiccon
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