原创力文档The distribution pattern of critically short telomeres in human osteoarthritic knees 英文参考文献.docVIP
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The distribution pattern of critically short telomeres in human osteoarthritic knees 英文参考文献
Harboetal.ArthritisResearchTherapy2012,14:R12
/content/14/1/R12
RESEARCH ARTICLE
OpenAccess
Thedistributionpatternofcriticallyshort
telomeresinhumanosteoarthriticknees
MariaHarbo1,2*,LailaBendix2,4,Anne-ChristineBay-Jensen1,JesperGraakjaer2,KentS?e1,ThomasLAndersen1,
PerKjaersgaard-Andersen3,SteenKoelvraa2,4 andJean-MarieDelaisse1
Abstract
Introduction:Telomereshorteningisassociatedwithanumberofcommonage-relateddiseases.Aroleof
telomereshorteninginosteoarthritis(OA)hasbeensuggested,mainlybasedontheassessmentofmeantelomere
lengthinexvivoexpandedchondrocytes.Weaddressedthisroledirectlyinvivo
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