The evolving clinical profile of abatacept (CTLA4–Ig) a novel co-stimulatory modulator for the treatment of rheumatoid arthritis 英文参考文献.docVIP

Available online /content/7/S2/S21 Review The evolving clinical profile of abatacept (CTLA4–Ig): a novel co-stimulatory modulator for the treatment of rheumatoid arthritis Eric M Ruderman and Richard M Pope Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA Corresponding author: Eric M Ruderman, e-ruderman@ Published: 16 March 2005 Arthritis Res Ther 2005, 7(Suppl 2):S21-S25 (DOI 10.1186/ar1688) ? 2005 BioMed Central Ltd Abstract response, and its effects are mediated by promoting proliferation and survival. Thus, therapies targeting c