The interferon type I signature towards prediction of non-response to rituximab in rheumatoid arthritis patients 英文参考文献.docVIP

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The interferon type I signature towards prediction of non-response to rituximab in rheumatoid arthritis patients 英文参考文献.doc

The interferon type I signature towards prediction of non-response to rituximab in rheumatoid arthritis patients 英文参考文献

Ratermanetal.ArthritisResearchTherapy2012,14:R95 /content/14/2/R95 RESEARCH ARTICLE OpenAccess TheinterferontypeIsignaturetowards predictionofnon-responsetorituximabin rheumatoidarthritispatients HennieGRaterman1?,SaskiaVosslamber2?,SanderdeRidder2,MichaelTNurmohamed3,WillemFLems1,3, MaartenBoers1,3,4,MarkvandeWiel4,BenACDijkmans1,3,CornelisLVerweij1,2* andAlexandreEVoskuyl1 Abstract Introduction:Bcelldepletiontherapyisefficaciousinrheumatoidarthritis(RA)patientsfailingontumornecrosis factor(TNF)blockingagents.However,approximately40%to50%ofrituximab(RTX)treatedRApatientshavea poorres

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