The lamin protein family 英文参考文献.docVIP

Dittmer and Misteli Genome Biology 2011,12:222 /2011/12/5/222 PROT EIN FA MILY RE VIE W The lamin protein family Travis Dittmer* and Tom Misteli including Arabidopsis thaliana, Saccharomyces cerevisiae and Schizosaccharomyces pombe. Summary The lamins are the major architectural proteins of the animal cell nucleus. Lamins line the inside of the nuclear membrane, where they provide a platform for the binding of proteins and chromatin and confer mechanical stability. They have been implicated in a wide range of nuclear functions, including higher- order genome organization, chromatin re