The L76V mutation in HIV-1 protease is potentially associated with hypersusceptibility to protease inhibitors Atazanavir and Saquinavir is there a clinical advantage 英文参考文献.docVIP

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The L76V mutation in HIV-1 protease is potentially associated with hypersusceptibility to protease inhibitors Atazanavir and Saquinavir is there a clinical advantage 英文参考文献.doc

The L76V mutation in HIV-1 protease is potentially associated with hypersusceptibility to protease inhibitors Atazanavir and Saquinavir is there a clinical advantage 英文参考文献

Wiesmannetal.AIDSResearchandTherapy2011,8:7 /content/8/1/7 SHORT REPORT OpenAccess TheL76VmutationinHIV-1proteaseispotentially associatedwithhypersusceptibilitytoprotease inhibitorsAtazanavirandSaquinavir:istherea clinicaladvantage? FrankWiesmann1*,JanVachta1,RobertEhret1,HaukeWalter2,RolfKaiser3,MartinStürmer4,AndréTappe5, MartinD?umer6,ThomasBerg7,GudrunNaeth1,PatrickBraun1,HeribertKnechten1 Abstract Background:AlthoughbeingconsideredasararelyobservedHIV-1proteasemutationinclinicalisolates,the L76V-prevalenceincreased1998-2008insomeEuropeancountriesmostlikelyduetotheapprovalofLopinavir, Am

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