The multiple functions of the endocannabinoid system a focus on the regulation of food intake 英文参考文献.docVIP

Tibiri?aDiabetologyMetabolicSyndrome2010,2:5 /content/2/1/5 DIABETOLOGY METABOLIC SYNDROME REVIEW OpenAccess Themultiplefunctionsoftheendocannabinoid system:afocusontheregulationoffoodintake EduardoTibiri?a* Abstract Background:Cannabissativa(alsoknownasmarijuana)hasbeencultivatedbymanformorethan5,000years. However,therewasariseinitsuseinthe20th centuryforrecreational,religiousorspiritual,andmedicinal purposes.Themainpsychoactiveconstituentofcannabis,whosestructurewasidentifiedinthe1960’s,isΔ9- tetrahydrocannabinol.Ontheotherhand,thediscoveryofcannabinoidreceptorsandtheirendogenousago