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The neuropeptide neuromedin U promotes autoantibody-mediated arthritis 英文参考文献
Raoetal.ArthritisResearchTherapy2012,14:R29
/content/14/1/R29
RESEARCH ARTICLE
OpenAccess
TheneuropeptideneuromedinUpromotes
autoantibody-mediatedarthritis
SindhujaMRao1,2?,JenniferLAuger1?,PhilippeGaillard3,RalphWeissleder4,EtsukoWada5,RichardTorres6,
MasayasuKojima7,ChristopheBenoist8,DianeMathis8andBryceABinstadt1*
Abstract
Introduction:NeuromedinU(NMU)isaneuropeptidewithpro-inflammatoryactivity.Theprimarygoalofthis
studywastodetermineifNMUpromotesautoantibody-inducedarthritis.Additionalstudiesaddressedthecellular
sourceofNMUandsoughttodefinetheNMUreceptorresponsibleforitspro-inflammator
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