The loss of health status in rheumatoid arthritis and the effect of biologic therapy a longitudinal observational study 英文参考文献.docVIP

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The loss of health status in rheumatoid arthritis and the effect of biologic therapy a longitudinal observational study 英文参考文献.doc

The loss of health status in rheumatoid arthritis and the effect of biologic therapy a longitudinal observational study 英文参考文献

WolfeandMichaudArthritisResearchTherapy2010,12:R35 /content/12/2/R35 RESEARCH ARTICLE OpenAccess Thelossofhealthstatusinrheumatoidarthritis andtheeffectofbiologictherapy:alongitudinal observationalstudy FrederickWolfe*,KalebMichaud Abstract Introduction:Thelong-termcourseofrheumatoidarthritis(RA)intermsofhealthstatusisnotwellunderstood, noristhedegreeofeffectivenessofbiologictherapyinthecommunity.Wemodeledtheprogressionoflossof healthstatus,andmeasuredincrementalcostsandeffectivenessofbiologictherapyinthecommunity. Methods:Westudiedchangeinfunctionandhealthstatusin18,485RApatients(135,731ob

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