The loss of health status in rheumatoid arthritis and the effect of biologic therapy a longitudinal observational study 英文参考文献.docVIP
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The loss of health status in rheumatoid arthritis and the effect of biologic therapy a longitudinal observational study 英文参考文献
WolfeandMichaudArthritisResearchTherapy2010,12:R35
/content/12/2/R35
RESEARCH ARTICLE
OpenAccess
Thelossofhealthstatusinrheumatoidarthritis
andtheeffectofbiologictherapy:alongitudinal
observationalstudy
FrederickWolfe*,KalebMichaud
Abstract
Introduction:Thelong-termcourseofrheumatoidarthritis(RA)intermsofhealthstatusisnotwellunderstood,
noristhedegreeofeffectivenessofbiologictherapyinthecommunity.Wemodeledtheprogressionoflossof
healthstatus,andmeasuredincrementalcostsandeffectivenessofbiologictherapyinthecommunity.
Methods:Westudiedchangeinfunctionandhealthstatusin18,485RApatients(135,731ob
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