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上海应用技术学院 毕业设计（论文） 课题名称的合成研究 系 (院) 香料香精技术与工程学院 班 级 学 号 0 姓 名 指导教师 起止日期 2011年月日至6月1日 的合成研究摘要：3位不同取代基的水杨酸酯。本论文实验分为2部分，第一部分以水杨酸甲酯为原料，分别与乙酰氯、异戊酰氯、正庚酰氯发生傅克酰基化反应，分别得到5-乙酰基水杨酸甲酯、5-异戊酰基水杨酸甲酯和5-庚酰基水杨酸甲酯；第二部分以水杨酸为原料，分别与甲醇、异丙醇、叔丁基发生傅克烷基化反应，分别得到3，53，53，5Abstract：The main purpose of salicylic acid esters as pharmaceutical and pesticide intermediates, spice and ultraviolet absorbers.In this thesis, a number of salicylic acid esters synthesized products, as well as methyl salicylate to salicylic acid as raw materials, Friedel-Crafts reactions, including alkylation and acylation reactions, the synthesis of three different substituents in the salicylidene esters.Experiments of this thesis is divided into two parts, the first part of the methyl salicylate as the raw material, respectively, with acetyl chloride, amyl chloride, heptane Friedel acyl chloride reaction occurred,were obtained 5-acetyl salicylic acid methyl ester, 5-acyl methyl salicylate and isoamyl 5-G acyl methyl salicylate.The second part of the salicylic acid as raw material, respectively, with methanol, isopropanol, tert-butyl Friedel-Crafts alkylation reaction occurred, respectively, by 3,5-dimethyl salicylic acid,3,5- diisopropyl salicylic acid and 3,5-ditertbutyl salicylic acid.More reaction steps and the temperature, time, optimize material feed ratio to choose the best process conditions Key Words: Acid esters; Friedel-Crafts reaction; Synthesis 目 录 1 绪论 1.1 二氢茉莉酮酸甲酯的合成研究 1 1.1.1 顺式-二氢茉莉酮酸甲酯 1 1.1.2 顺式-二氢茉莉酮酸甲酯的合成..................................................................................................1 1.2 水杨酸酯类产品 4 1.2.1 水杨酸酯类产品制法及用途 4 1.2.2 水杨酸酯类的产品介绍 4 1.3 傅克反应概述........................................................................................................................................5 1.3.1傅克烷基化反应 .6 1.3.2 傅克酰基化反应...........................................