Using orthologous and paralogous proteins to identify specificity determining residues 英文参考文献.docVIP

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Using orthologous and paralogous proteins to identify specificity determining residues 英文参考文献.doc

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Using orthologous and paralogous proteins to identify specificity determining residues 英文参考文献

/2002/3/3/preprint/0002.1 This information has not been peer-reviewed. Responsibility for the findings rests solely with the author(s). Deposited research article Using orthologous and paralogous proteins to identify specificity determining residues Leonid A. Mirny* and Mikhail S. Gelfand? Addresses: *Harvard-MIT Division of Health Science and Technology, Massachusetts Institute of Technology, 77 Massachusetts ave, Cambridge, MA 02139.?IntegratedGenomics-Moscow, P.O.Box 348, Moscow, 117333, Russia. Correspondence: Leonid A. Mirny. E-mail: leonid@ Posted: 19 February 2002 Received: 13 February 2002 Genome Biology 2002, 3(3):preprint0002.1-0002.20 The electronic version of this article is the complete one and can be found online at /2002/3/3/preprint/0002 This is the first version of this article to be made available publicly. ? BioMed Central Ltd (Print ISSN 1465-6906; Online ISSN 1465-6914) .deposited research AS A SERVICE TO THE RESEARCH COMMUNITY, GENOME BIOLOGY PROVIDES A PREPRINT DEPOSITORY TO WHICH ANY ORIGINAL RESEARCH CAN BE SUBMITTED AND WHICH ALL INDIVIDUALS CAN ACCESS FREE OF CHARGE. ANY ARTICLE CAN BE SUBMITTED BY AUTHORS, WHO HAVE SOLE RESPONSIBILITY FOR THE ARTICLES CONTENT. THE ONLY SCREENING IS TO ENSURE RELEVANCE OF THE PREPRINT TO GENOME BIOLOGYS SCOPE AND TO AVOID ABUSIVE, LIBELLOUS OR INDECENT ARTICLES. ARTICLES IN THIS SECTION OF THE JOURNAL HAVE NOT BEEN PEER-REVIEWED. EACH PREPRINT HAS A PERMANENT URL, BY WHICH IT CAN BE CITED. RESEARCH SUBMITTED TO THE PREPRINT DEPOSITORY MAY BE SIMULTANEOUSLY OR SUBSEQUENTLY SUBMITTED TO GENOME BIOLOGY OR ANY OTHER PUBLICATION FOR PEER REVIEW; THE ONLY REQUIREMENT IS AN EXPLICIT CITATION OF, AND LINK TO, THE PREPRINT IN ANY VERSION OF THE ARTICLE THAT IS EVENTUALLY PUBLISHED. IF POSSIBLE, GENOME BIOLOGY WILL PROVIDE A RECIPROCAL LINK FROM THE PREPRINT TO THE PUBLISHED ARTICLE. 2 GenomeBiology Depositedresearch(preprint) Using orthologous and paralogous protei