原创力文档Sequence selectivity of macrolide-induced translational attenuation
Sequence selectivity of macrolide-induced
translational attenuation
Amber R. Davis, David W. Gohara, and Mee-Ngan F. Yap1
Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO 63104
Edited by Jennifer A. Doudna, University of California, Berkeley, CA, and approved September 18, 2014 (received for review June 3, 2014)
The prevailing “plug-in-the-bottle” model suggests that macrolide presence of the macrolide azithromycin (AZ). In addition to
antibiotics inhibit translation by binding inside the
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