Theeffectivetreatmentofacne.PDFVIP

J Cosmetic Laser Ther 2003; 5: 111–116 # J Cosmetic Laser Ther. All rights reserved ISSN 1476-4172 DOI: 10.1080/14764170310001276 111 Original Research The effective treatment of acne vulgaris by a high-intensity, narrow band 405–420 nm light source Monica Elman, Michael Slatkine Yoram Harth BACKGROUND: Available topical treat- full-face open trial and the split-face, Authors: ments are slow and frequently irritat- double-blind controlled study. The Monica Elman, MD ing. Oral therapies may be associated studies enrolled 10, 13 and 23 Beit Harofim Holon, Israel with increased bacterial resistance patients respectively. Michael Slatkine, PhD (antibiotics) or possible severe side RESULTS: The data show more than CureLight Ltd Or Akiva, Israel effects (oral isotretinoin). In vitro and an 80% response to 420 nm acne Yoram Harth, MD in vivo exposure of acne bacteria to phototherapy with a significant Elisha Medical Center Haifa, Israel 405–420 nm ultraviolet (UV) free blue reduction of 59–67% of inflamma- light results in the photo-destruction tory acne lesions after only eight Received 27 June 2002 of these bacteria through the effects treatments of 8–15 minutes. The Accepted 27 November 2002 on the porphyrins produced naturally reduction in les